Misa Fujisawa grapples with monthly bouts of premenstrual syndrome, struggling to control her irritation towards colleagues at work. When her anger erupts at newcomer Takatoshi Yamazoe over a minor incident, she spirals into self-hatred. Meanwhile, Takatoshi battles panic disorder, leading a lethargic life. As they become aware of each other's struggles, Misa and Takatoshi form a bond, endeavoring to support one another through their respective challenges.
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